Pharmacological Screening and Evaluation of Antiplasmodial Activity of Gongronema latifolium (utazi) Against Plasmodium berghei berghei infection in Mice

@article{Etetim2009PharmacologicalSA,
  title={Pharmacological Screening and Evaluation of Antiplasmodial Activity of Gongronema latifolium (utazi) Against Plasmodium berghei berghei infection in Mice},
  author={En Etetim and M. Useh and J. Okokon},
  journal={Nigerian Journal of Health and Biomedical Sciences},
  year={2009},
  volume={7},
  pages={51-55}
}
The antiplasmodial activity of the ethanolic leaf extract of Gongronema latifolium on chloroquine-sensitive Plasmodium berghi berghi infection in mice was investigated in Calabar, Nigeria to assess its traditional use as an antimalarial remedy in Nigeria. The schizonticidal activity of the extract and that of chloroquine were determined in mice. The pharmacological property of the leaf was also assessed using standard procedures. The LD­50 of the extract was estimated using Swiss Albino mice by… Expand
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