Pharmacological Modulation of Cardiovascular Remodeling: A Guide to Heart Failure Therapy

@article{Remme2003PharmacologicalMO,
  title={Pharmacological Modulation of Cardiovascular Remodeling: A Guide to Heart Failure Therapy},
  author={Willem J. Remme},
  journal={Cardiovascular Drugs and Therapy},
  year={2003},
  volume={17},
  pages={349-360}
}
Cardiac remodeling is a complex process, which involves genetic, molecular and cellular changes in cardiomyocytes and the interstitium, leading to progressive structural and functional alterations, including cardiac dilatation, interstitial fibrosis, and a reduction in contractility and relaxation. As cardiac function worsens, ventricular dysfunction, heart failure and end-stage heart disease are the ultimate consequences. Underlying mechanisms include myocardial stretch and neurohormonal and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Which Beta-Blocker is Most Effective in Heart Failure?

Cardiovascular Drugs and Therapy • 2010
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 100 references

Does baseline heart rate determine the effect of carvedilol on ventricular remodeling in heart failure? Results of the CARMEN (Carvedilol Ace inhibitor Remodeling Mild heart failure EvaluatioN) Study

WJ Remme, G Riegger, L Ryden
Eur Heart J 2003;24(abstract-suppl.):711 • 2003
View 1 Excerpt

Similar Papers

Loading similar papers…