Pharmacologic strategies for the prevention of atherosclerotic plaque progression.

  title={Pharmacologic strategies for the prevention of atherosclerotic plaque progression.},
  author={Paul Schoenhagen and Timothy D. Crowe and Murat E Tuzcu and Steven E. Nissen},
  journal={Expert review of cardiovascular therapy},
  volume={2 6},
Despite improved treatment options, coronary artery disease remains the leading cause of death in men and women in industrialized societies. Reduction of atherosclerotic disease will require the development and evaluation of new classes of pharmacologic agents capable of modifying the development and progression of the atherosclerotic disease process. The direct observation of coronary plaque burden and morphology with in vivo imaging modalities has been evaluated as an end point in serial… CONTINUE READING