Pharmacologic management of the opioid neonatal abstinence syndrome.

  title={Pharmacologic management of the opioid neonatal abstinence syndrome.},
  author={Walter K Kraft and Johannes N van den Anker},
  journal={Pediatric clinics of North America},
  volume={59 5},
Opioid use in pregnant women has increased over the last decade. Following birth, infants with in utero exposure demonstrate signs and symptoms of withdrawal known as the neonatal abstinence syndrome (NAS). Infants express a spectrum of disease, with most requiring the administration of pharmacologic therapy to ensure proper growth and development. Treatment often involves prolonged hospitalization. There is a general lack of high-quality clinical trial data to guide optimal therapy, and… CONTINUE READING
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