Pharmacologic Use of Niacin

  title={Pharmacologic Use of Niacin},
  author={Jonathan E. Prousky and Christine G. Millman and J. B. Kirkland},
  journal={Complementary Health Practice Review},
  pages={101 - 91}
  • Jonathan E. Prousky, Christine G. Millman, J. B. Kirkland
  • Published 2011
  • Biology
  • Complementary Health Practice Review
  • Niacin is required for a host of critical redox and adenosine diphosphate-ribosylation reactions in metabolism. Niacin deficiency leads to the distinctive signs and symptoms of pellagra, but these can happen in an unpredictable progression and can be altered in patients with polymorphisms in any of the hundreds of niacin-dependent enzymes. The symptomatology of niacin deficiency is becoming a forgotten knowledge base, and niacin deficiency is likely underdiagnosed. Additionally, high levels of… CONTINUE READING
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