Cocaine abuse: historical, epidemiological, and psychological perspectives.
- H D Kleber
- The Journal of clinical psychiatry
The rapid escalation of cocaine abuse in the United States in the 1980 's has generated a host of inte rest ing hypotheses on various aspect s of th is problem. After a succinct discussion of epidemiologic, clinical , and neuro-pharmacologic aspects of cocaine abuse, a survey of the current literature on psych ophar macologic management of dependence is offere d . While several agents ha ve emerged as usefu l adj unc tive treatments for abstinence syndromes it is important for the cli nic ian to remember that th ere is not official approval for such treatments. Additionally, psyc hotherapeutic maneuvers, which remain th e major tools in treatment ofaddicts, should not be overlooked when an experimental pharmacologic intervention is selected.