Pharmacokinetis of alpha- and beta-isomers of racemic endosulfan following intravenous administration in rabbits.

@article{Gupta1979PharmacokinetisOA,
  title={Pharmacokinetis of alpha- and beta-isomers of racemic endosulfan following intravenous administration in rabbits.},
  author={Praveen Kumar Gupta and Mats Ehrnebo},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  year={1979},
  volume={7 1},
  pages={7-10}
}
The pharmacokinetics of the alpha- and beta-isomers of endosulfan in rabbits was investigated following intravenous injection. Endosulfan (2 mg/kg) was given as a mixture of the two isomers in the ratio 70:30. The plasma concentration-time data for alpha-endosulfan was best fitted to the three-compartment model with a terminal slope half-life of 235 +/- 168… CONTINUE READING