Pharmacokinetics of vinyl chloride in the Rhesus monkey.

  title={Pharmacokinetics of vinyl chloride in the Rhesus monkey.},
  author={A. Buchter and Johannes Georg Filser and H. -H. Peter and Hermann Maximillian Bolt},
  journal={Toxicology letters},
  volume={6 1},
The metabolic elimination of vinyl chloride in Rhesus monkeys is a dose-dependent, satruable process, as in rats. Below 200-300 ppm of vinyl chloride (VC) in atmosphere, elimination obeys a first-order law; the clearance rate is much closer to that found in man than the values for rats, mice and gerbils. The maximal velocity of metabolic elimination of VC… CONTINUE READING