Pharmacokinetics of the dermal route of exposure to volatile organic chemicals in water: a computer simulation model.

Abstract

A kinetic model of dermal absorption of nonpolar organic nonelectrolytes in dilute aqueous solutions is described. The model uses systems dynamics STELLA software and is designed for a Macintosh computer. The model assumes the outer stratum corneum layer of skin to be the rate-determining barrier to dermal absorption and assumes that both stratum corneum… (More)

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Cite this paper

@article{Shatkin1991PharmacokineticsOT, title={Pharmacokinetics of the dermal route of exposure to volatile organic chemicals in water: a computer simulation model.}, author={Jo Anne Shatkin and Heather Brown}, journal={Environmental research}, year={1991}, volume={56 1}, pages={90-108} }