Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.

@article{Lee2002PharmacokineticsOT,
  title={Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.},
  author={M J Lee and Pius Maliakal and Laishun Chen and Xiaofeng Meng and Flordeliza Y. Bondoc and S Lakshimi Prabhu and George H. Lambert and Sandra N Mohr and Chung S Yang},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2002},
  volume={11 10 Pt 1},
  pages={
          1025-32
        }
}
Green tea and tea polyphenols have been studied extensively as cancer chemopreventive agents in recent years. The bioavailability and metabolic fate of tea polyphenols in humans, however, are not clearly understood. In this report, the pharmacokinetic parameters of (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin (EGC), and (-)-epicatechin (EC) were analyzed after administration of a single oral dose of green tea or decaffeinated green tea (20 mg tea solids/kg) or EGCG (2 mg/kg) to… CONTINUE READING
Highly Influential
This paper has highly influenced 20 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 218 extracted citations

Effect of a single dose of green tea polyphenols on the blood markers of exercise-induced oxidative stress in soccer players.

International journal of sport nutrition and exercise metabolism • 2012
View 4 Excerpts
Highly Influenced

Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?

International journal of molecular sciences • 2011
View 7 Excerpts
Highly Influenced

Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases

Advances in Experimental Medicine and Biology • 2015
View 1 Excerpt
Highly Influenced

Similar Papers

Loading similar papers…