Pharmacokinetics of sulfamethoxazole and trimethoprim in donkeys, mules, and horses.

Abstract

OBJECTIVE To compare serum disposition of sulfamethoxazole and trimethoprim after IV administration to donkeys, mules, and horses. ANIMALS 5 donkeys, 5 mules, and 3 horses. PROCEDURE Blood samples were collected before (time 0) and 5, 15, 30, and 45 minutes and 1, 1.25, 1.5, 1.75, 2, 2.5, 3, 3.5, 4, 4.5, 5, 6, 8, 10, and 24 hours after IV administration… (More)

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