Pharmacokinetics of reboxetine enantiomers in the dog.

  title={Pharmacokinetics of reboxetine enantiomers in the dog.},
  author={Enrico Frigerio and A Benecchi and G Brianceschi and Cinzia Pellizzoni and Italo Poggesi and M S Strolin Benedetti and Philippe Dostert},
  volume={9 3},
Reboxetine, (RS)-2-[(RS)-alpha-(2-ethoxyphenoxy)benzyl]morpholine methanesulphonate, is a racemic compound and consists of a mixture of the (R,R)- and (S,S)-enantiomers. The pharmacokinetics of reboxetine enantiomers were determined in a crossover study in three male beagle dogs. Each animal received the following oral treatments, separated by 1-week… CONTINUE READING