Pharmacokinetics of parenteral and oral melperone in man

  title={Pharmacokinetics of parenteral and oral melperone in man},
  author={L. Borgstr{\"o}m and H. Larsson and L. Molander},
  journal={European Journal of Clinical Pharmacology},
  • L. Borgström, H. Larsson, L. Molander
  • Published 2004
  • Medicine
  • European Journal of Clinical Pharmacology
  • SummaryThe pharmacokinetics of melperone (Buronil®, Ferrosan, Sweden) was studied after administration of various parenteral and oral doses to man. After parenteral administration, the data could be fitted to a two-compartment model, but after oral dosing the distribution phase could not be separated from the elimination phase, and so an one-compartment model gave the best fit. The half-lives were about 3–4 h, except after intramuscular injection, when the half-life was about 6 h. The… CONTINUE READING

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