Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy

Abstract

The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) of p-aminohippuric acid (PAH) and inulin, New Zealand white rabbits were used in this study. The plasma concentrations of… (More)
DOI: 10.1155/2011/204501

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@inproceedings{Tseng2011PharmacokineticsOP, title={Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy}, author={Chiao-Shih Tseng and Shih-Ming Chen and Shu-Chen Chien and Kuang-Yang Hsu}, booktitle={Advances in pharmacological sciences}, year={2011} }