Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever.

Abstract

The pharmacokinetics of oral and intravenous ofloxacin (7.5 mg.kg of body weight-1 given over 30 min) were studied in an open crossover study of 17 Vietnamese children, aged between 5 and 14 years, with acute uncomplicated typhoid fever. Following oral administration, the median (95% confidence interval [CI]) time to peak concentration of ofloxacin in serum… (More)

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Cite this paper

@article{Bethell1996PharmacokineticsOO, title={Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever.}, author={Delia B Bethell and N P J Day and Nguyen Minh Dung and Cari McMullin and Ha Thi Loan and Daniel Tam and Luong The Minh and Nguyen Thi Truc Linh and Nguyen Quang Dung and H. Vinh and Alasdair P Macgowan and Leslie O White and Nicholas J White}, journal={Antimicrobial agents and chemotherapy}, year={1996}, volume={40 9}, pages={2167-72} }