Pharmacokinetics of multiple intravenous instillation of levofloxacin in Chinese healthy subjects.

@article{Zhang2002PharmacokineticsOM,
  title={Pharmacokinetics of multiple intravenous instillation of levofloxacin in Chinese healthy subjects.},
  author={Li Zhang and Jia-tai Li and Y. Q. Lu and Man-Ning Li and Yong-Long Zhang and Yan Liu and Tian-yun Li and Jian-Wei Zhang},
  journal={Acta pharmacologica Sinica},
  year={2002},
  volume={23 4},
  pages={381-4}
}
AIM To study the pharmacokinetics of multiple doses intravenous infusion of levofloxacin instillation in Chinese healthy volunteers. METHODS Intravenous infusion of levofloxacin instillation 200 mg within 60 min was given to 10 male healthy volunteers for 7 d, on d 1 and d 7, once-daily, from 2-6 d twice-daily dosing. The concentrations of levofloxacin in serum and urine were assayed by HPLC. RESULTS The main pharmacokinetic parameters af ter the first dosing were as follows: Cmax was (2.4… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…