Pharmacokinetics of mitragynine in man

  title={Pharmacokinetics of mitragynine in man},
  author={Satariya Trakulsrichai and Korbtham Sathirakul and Saranya Auparakkitanon and Jatupon Krongvorakul and Jetjamnong Sueajai and Nantida Noumjad and Chonlaphat Sukasem and Winai Wananukul},
  booktitle={Drug design, development and therapy},
BACKGROUND Kratom, known botanically as Mitragyna speciosa (Korth.), is an indigenous tree in Southeast Asia. Kratom is currently easily available worldwide via special shops and the Internet to use as a drug of abuse, opioid alternative, or pain killer. So far, the pharmacokinetics of this plant has been studied only in animals, and there is no such study in humans. The major abundant active alkaloid in Kratom, mitragynine, is one of the promising new chemical substances to be developed as a… CONTINUE READING