Pharmacokinetics of micafungin in subjects with severe hepatic dysfunction

@inproceedings{Undre2014PharmacokineticsOM,
  title={Pharmacokinetics of micafungin in subjects with severe hepatic dysfunction},
  author={Nasrullah Undre and Benjamin Pretorius and Paul Stevenson},
  booktitle={European Journal of Drug Metabolism and Pharmacokinetics},
  year={2014}
}
Micafungin is an echinocandin with potent activity against a broad range of fungal species, including Candida species. The pharmacokinetic and safety profiles of micafungin have been evaluated in individuals with mild-to-moderate hepatic dysfunction, but not in individuals with severe hepatic dysfunction. Therefore, the present study assessed the… CONTINUE READING