Pharmacokinetics of micafungin in HIV positive patients with confirmed esophageal candidiasis

  title={Pharmacokinetics of micafungin in HIV positive patients with confirmed esophageal candidiasis},
  author={Nas Undre and Paul Stevenson and Ezio Baraldi},
  journal={European Journal of Drug Metabolism and Pharmacokinetics},
Esophageal candidiasis (EC) is a common and serious complication in patients infected with the human immunodeficiency virus (HIV). Micafungin has been shown to have dose-related efficacy and to be well tolerated in patients with HIV and EC. This analysis of data from a randomized, double-blind study examined pharmacokinetic parameters of micafungin (dosed at 50, 100, and 150 mg/day) and its metabolites in a subset of patients with HIV and EC. Micafungin exhibited linear, predictable… CONTINUE READING
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