Pharmacokinetics of meropenem in patients with renal failure and patients receiving renal replacement therapy.

@article{Thalhammer2000PharmacokineticsOM,
  title={Pharmacokinetics of meropenem in patients with renal failure and patients receiving renal replacement therapy.},
  author={Florian Thalhammer and Walter Hermann H{\"o}rl},
  journal={Clinical pharmacokinetics},
  year={2000},
  volume={39 4},
  pages={271-9}
}
Meropenem is a well established carbapenem antibacterial with a wide spectrum of activity against Gram-positive and Gram-negative bacteria, including beta-lactamase producers and Pseudomonas aeruginosa. Because of its clinical and bacteriological efficacy, meropenem is an important antimicrobial drug in the treatment of serious infections in adults and in children. Meropenem is predominately excreted unchanged in the urine, and thus dosage adjustments are necessary in patients with renal… CONTINUE READING
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