Pharmacokinetics of meloxicam following intravenous and oral administration in green iguanas (Iguana iguana).

@article{Divers2010PharmacokineticsOM,
  title={Pharmacokinetics of meloxicam following intravenous and oral administration in green iguanas (Iguana iguana).},
  author={Stephen John Divers and Mark D Papich and Michael McBride and Nancy L. Stedman and David Perpi{\~n}{\'a}n and Thomas F Koch and Sonia M. Hernandez and Grace Heather Wilson Barron and Melinda Pethel and Steven Budsberg},
  journal={American journal of veterinary research},
  year={2010},
  volume={71 11},
  pages={1277-83}
}
OBJECTIVE To determine pharmacokinetics of meloxicam in healthy green iguanas following PO and IV administration and assess potential toxicity. ANIMALS 21 healthy green iguanas (Iguana iguana). PROCEDURES To assess pharmacokinetics, 13 iguanas were administered a single dose (0.2 mg/kg) of meloxicam PO and, 14 days later, the same dose IV. To assess potential toxicity, 4 iguanas were given meloxicam at a dosage of 1 or 5 mg/kg, PO, every 24 hours for 12 days, and results of histologic… CONTINUE READING