Pharmacokinetics of medetomidine.

  title={Pharmacokinetics of medetomidine.},
  author={Jarmo S. Salonen},
  journal={Acta veterinaria Scandinavica. Supplementum},
The pharmacokinetics of medetomidine administered as a single dose (80 micrograms/kg) were studied in rat, dog and cat with the tritium labelled drug. The results showed a rapid distribution, after an s.c. dose, of medetomidine radioactivity into rat tissues including the brains. In plasma/serum a distribution phase with a half-life of only a few minutes was observed. Peak concentration after i.m. administration (dog & cat) was seen within 0.5 h in complete accordance with the rapid onset of… CONTINUE READING
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