Pharmacokinetics of lansoprazole in hemodialysis patients.

  title={Pharmacokinetics of lansoprazole in hemodialysis patients.},
  author={M D Karol and J M Machinist and John M. Cavanaugh},
  journal={Journal of clinical pharmacology},
  volume={35 8},
The pharmacokinetics of the new benzimidazole proton pump inhibitor lansoprazole and five of its metabolites were assessed after single oral dose administration to five hemodialysis patients. Patients were studied on dialysis and nondialysis days. Multiple blood and dialysate samples were collected after dosing and were assayed for lansoprazole and… CONTINUE READING