Pharmacokinetics of ketoprofen following oral and intramuscular administration in young children

@article{Kokki2001PharmacokineticsOK,
  title={Pharmacokinetics of ketoprofen following oral and intramuscular administration in young children},
  author={Hannu Kokki and H. Tuomilehto and Marko Karvinen},
  journal={European Journal of Clinical Pharmacology},
  year={2001},
  volume={57},
  pages={643-647}
}
Objective: The pharmacokinetics of ketoprofen following intramuscular injection or oral tablet was determined in children aged 10–69 months. Methods: Ten children received a single intramuscular injection of 1 mg kg–1 ketoprofen. Six children, weight 12–17 kg, received a 12.5-mg ketoprofen tablet and four children, weight 18–23 kg, received a 25-mg tablet. Venous blood samples were collected at 15 min and 30 min and 1, 2, 4, 6 and 8 h following drug dosing. Plasma ketoprofen levels were… CONTINUE READING

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