Pharmacokinetics of ivermectin in the yak (Bos grunniens).

@article{Dupuy2003PharmacokineticsOI,
  title={Pharmacokinetics of ivermectin in the yak (Bos grunniens).},
  author={Jacques Dupuy and Hong Yin and Jamie X. Luo and Dongya Y. Yang and Gui Quan Guan and Mi Ling Ma and J. F. Sutra and Anne Lespine and Chantal Boulard and Michel Alvinerie},
  journal={Veterinary parasitology},
  year={2003},
  volume={117 1-2},
  pages={153-7}
}
The yak (Bos grunniens) belongs to the cattle family Bovidae and lives in the mountains of China and adjacent areas. Due to the physiological adaptations of yak to its environment and the lack of data, the ivermectin pharmacokinetic was studied following a single subcutaneous dose at the recommended dose for cattle (0.2 mg kg(-1)). The observed peak plasma concentration (Cmax) was 48.93 ng ml(-1) and the time to reach Cmax (Tmax) was 0.73 day. These results show a faster rate of absorption than… CONTINUE READING

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