Pharmacokinetics of itraconazole oral solution in neutropenic children during long-term prophylaxis.

@article{Schmitt2001PharmacokineticsOI,
  title={Pharmacokinetics of itraconazole oral solution in neutropenic children during long-term prophylaxis.},
  author={Claudine Schmitt and Yves P{\'e}rel and J. L. Harousseau and Sophie Lemerle and Elisabeth Chwetzoff and Jean-Pierre Le Moing and J. C. Levron},
  journal={Antimicrobial agents and chemotherapy},
  year={2001},
  volume={45 5},
  pages={1561-4}
}
We investigated the pharmacokinetics and safety of an oral solution of itraconazole in two groups of neutropenic children stratified by age. Effective concentrations of itraconazole in plasma were reached quickly and maintained throughout treatment. The results indicate a trend toward higher concentrations of itraconazole in plasma in older children. 

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