Pharmacokinetics of intravenous ceftiofur sodium and concentration in body fluids of foals.

@article{Meyer2009PharmacokineticsOI,
  title={Pharmacokinetics of intravenous ceftiofur sodium and concentration in body fluids of foals.},
  author={Silke Meyer and Steeve Gigu{\`e}re and R Rodriguez and Raymond J Zielinski and Geetanjali Grover and Scott A. Brown},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2009},
  volume={32 4},
  pages={309-16}
}
The objectives of this study were to determine pharmacokinetics of intravenous (i.v.) ceftiofur in foals, to compare ultra-high performance liquid chromatography tandem mass spectometry (UPLC-MS/MS) and microbiologic assay for the measurement of ceftiofur concentrations, and to determine the minimum inhibitory concentration (MIC) of ceftiofur against common equine bacterial pathogens. In a cross-over design, ceftiofur sodium was administered i.v. to six foals (1-2 days-of-age and 4-5 weeks-of… CONTINUE READING