Pharmacokinetics of florfenicol in veal calves.

@article{Varma1986PharmacokineticsOF,
  title={Pharmacokinetics of florfenicol in veal calves.},
  author={Kanwal J Varma and Portia Adams and Timothy E Powers and J D Powers and J F Lamendola},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={1986},
  volume={9 4},
  pages={412-25}
}
The pharmacokinetic disposition of florfenicol was described in veal calves after administration of a single 22-mg/kg dose intravenously, orally after a 12-h fast and orally 5 min post feeding. Both serum concentrations and urinary excretion were studied. After intravenous administration the median elimination half-life was 171.9 min while the half-life of the distribution phase was 5.9 min. The median body clearance (Cl) and apparent volume of distribution (Vz) were 2.85 ml/kg/min and 0.78 l… CONTINUE READING

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