Corpus ID: 20904697

Pharmacokinetics of falintolol II. Absorption, distribution and elimination from tissues and organs following ocular administration and intravenous injection of falintolol in albino rabbits.

@article{Andermann1989PharmacokineticsOF,
  title={Pharmacokinetics of falintolol II. Absorption, distribution and elimination from tissues and organs following ocular administration and intravenous injection of falintolol in albino rabbits.},
  author={G. Andermann and P. Guggenbuhl and G. de Burlet and J. Himber},
  journal={Methods and findings in experimental and clinical pharmacology},
  year={1989},
  volume={11 12},
  pages={
          747-54
        }
}
The absorption, distribution and elimination of falintolol maleate was studied in various ocular and extraocular tissues and organs following ocular instillation, intravenous injection of a 0.5% 14C-falintolol ophthalmic solution and repeated ocular instillations of a 1% non-labeled falintolol ophthalmic solution into albino New Zealand rabbits. Falintolol was distributed in all studied tissues and organs after both routes of administration. After ocular instillation, levels of total… Expand
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