Pharmacokinetics of erythromycin in nonlactating and lactating goats after intravenous and intramuscular administration.

@article{Ambros2007PharmacokineticsOE,
  title={Pharmacokinetics of erythromycin in nonlactating and lactating goats after intravenous and intramuscular administration.},
  author={Luis A Ambros and Laura Montoya and Ver{\'o}nica Kreil and Samanta Waxman and Gabriela A Albarellos and Marcela Rebuelto and Ruben Hallu and Manuel Ignacio San Andr{\'e}s},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2007},
  volume={30 1},
  pages={80-5}
}
The objectives of this work were to compare the pharmacokinetics of erythromycin administered by the intramuscular (i.m.) and intravenous (i.v.) routes between nonlactating and lactating goats and to determine the passage of the drug from blood into milk. Six nonpregnant, nonlactating and six lactating goats received erythromycin by the i.m. (15 mg/kg) and the i.v. (10 mg/kg) routes of administration. Milk and blood samples were collected at predetermined times. Erythromycin concentrations were… CONTINUE READING