Pharmacokinetics of epirubicin in man. Non-influence of alpha interferon.

@article{Eksborg1988PharmacokineticsOE,
  title={Pharmacokinetics of epirubicin in man. Non-influence of alpha interferon.},
  author={Staffan Eksborg and Karin V Mattson},
  journal={Medical oncology and tumor pharmacotherapy},
  year={1988},
  volume={5 2},
  pages={
          131-3
        }
}
The influence of alpha interferon on the plasma pharmacokinetics of epirubicin has been studied in five patients with bronchial cancer. The pharmacokinetic studies of epirubicin (100 mg m-2) were performed prior to and immediately after a 3 wk period with daily natural alpha interferon treatment (6 x 10(6) IU i.m.). None of the patients had been treated with antracyclines or interferon prior to entering the present study. The plasma pharmacokinetics of epirubicin were most adequately described… CONTINUE READING
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