Pharmacokinetics of epirubicin in man. Non-influence of alpha interferon.

  title={Pharmacokinetics of epirubicin in man. Non-influence of alpha interferon.},
  author={Staffan Eksborg and Karin V Mattson},
  journal={Medical oncology and tumor pharmacotherapy},
  volume={5 2},
The influence of alpha interferon on the plasma pharmacokinetics of epirubicin has been studied in five patients with bronchial cancer. The pharmacokinetic studies of epirubicin (100 mg m-2) were performed prior to and immediately after a 3 wk period with daily natural alpha interferon treatment (6 x 10(6) IU i.m.). None of the patients had been treated with antracyclines or interferon prior to entering the present study. The plasma pharmacokinetics of epirubicin were most adequately described… CONTINUE READING