Pharmacokinetics of enrofloxacin following intravenous and intramuscular administration in Angora rabbits.

@article{Elmas2007PharmacokineticsOE,
  title={Pharmacokinetics of enrofloxacin following intravenous and intramuscular administration in Angora rabbits.},
  author={Muammer Elmas and Kamil Uney and Enver Yazar and Ayse Karabacak and B{\"u}nyamin Traş},
  journal={Research in veterinary science},
  year={2007},
  volume={82 2},
  pages={242-5}
}
The pharmacokinetic behaviour and bioavailability of enrofloxacin (ENR) were determined after single intravenous (iv) and intramuscular (im) administrations of 5mg/kg bw to six healthy adult Angora rabbits. Plasma ENR concentrations were measured by high performance liquid chromatography. The pharmacokinetic data were best described by a two-compartment open model. ENR pharmacokinetic parameters were similar (p>0.05) for iv and im administrations in terms of AUC0-infinity, t1/2beta and MRT. ENR… CONTINUE READING

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