Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and intramuscular administrations in sheep.

@article{Mengozzi1996PharmacokineticsOE,
  title={Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and intramuscular administrations in sheep.},
  author={Grazia Mengozzi and Luigi Intorre and Simone Bertini and Giulio Soldani},
  journal={American journal of veterinary research},
  year={1996},
  volume={57 7},
  pages={1040-3}
}
OBJECTIVE To evaluate the pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after administrations of enrofloxacin in sheep. DESIGN Crossover study performed by i.v. and i.m. administrations of 2.5 mg of enrofloxacin/kg of body weight to 2 groups of 3 sheep. After a 15-day resting period, the drug administration was repeated, using the alternative route. ANIMALS 6 clinically normal Massese sheep of either sex. PROCEDURE Blood samples were collected at suitable intervals… CONTINUE READING

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