Pharmacokinetics of diminazene in female Boran (Bos indicus) cattle.

@article{Aliu1993PharmacokineticsOD,
  title={Pharmacokinetics of diminazene in female Boran (Bos indicus) cattle.},
  author={Yusuf Otaru Aliu and Mohammed Mamman and Andrew S. Peregrine},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={1993},
  volume={16 3},
  pages={
          291-300
        }
}
The disposition kinetics and bioavailability of diminazene in five healthy heifers were determined after single intravenous (i.v.) and intramuscular (i.m.) administration of the drug in sequence with a wash-out period between administrations of 6 weeks. Intact diminazene in plasma, whole blood and urine samples was analysed using high-performance liquid chromatography. Nonlinear regression analysis of the i.v. and i.m. data indicated that, for either route, the plasma disappearance curves of… CONTINUE READING

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