Pharmacokinetics of ceftriaxone in serum and gynecological tissues.

@article{Grandi1986PharmacokineticsOC,
  title={Pharmacokinetics of ceftriaxone in serum and gynecological tissues.},
  author={Pierre de Grandi and J F Bauen},
  journal={Chemotherapy},
  year={1986},
  volume={32 6},
  pages={
          473-7
        }
}
In order to evaluate the pharmacokinetics of ceftriaxone (Rocephin) in serum and gynecological tissues, intravenous injections of 2 g of ceftriaxone were administered to 3 groups, numbering 6 patients each, at 2-, 12-, and 24-hour intervals prior to surgery (hysterectomy and annexectomy) for noninfectious pathology. Even 24 h after intravenous administration of 2 g of ceftriaxone, both serum and gynecological tissue concentrations are well above the MIC90 for the majority of pathogens… CONTINUE READING