Pharmacokinetics of cefepime during continuous venovenous hemodiafiltration.

@article{Allaouchiche1997PharmacokineticsOC,
  title={Pharmacokinetics of cefepime during continuous venovenous hemodiafiltration.},
  author={Bernard Allaouchiche and Dominique Breilh and H. Jaumain and B{\'e}n{\'e}dicte Gaillard and Stanislas Renard and Marie Claude Saux},
  journal={Antimicrobial agents and chemotherapy},
  year={1997},
  volume={41 11},
  pages={
          2424-7
        }
}
The objective of this study was to analyze the pharmacokinetics of cefepime, in six patients with acute renal failure related to septic shock, during continuous venovenous hemodiafiltration (CVVHD) (Hemospal AN 69S hemofilter; Hospal, Lyon, France). Six patients, mean age 65 +/- 4 years (range, 61 to 69), were included and each received 2 g of cefepime by intravenous infusion over a 30-min period every 12 h. Prefilter serum, dialysate outlet (DO), and ultrafiltrate samples were collected 0.47… CONTINUE READING

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