Pharmacokinetics of antituberculosis drugs in patients.

  title={Pharmacokinetics of antituberculosis drugs in patients.},
  author={Zafar Hasan Israili and Christopher M Rogers and H M el-Attar},
  journal={Journal of clinical pharmacology},
  volume={27 1},
The pharmacokinetics of rifampin, isoniazid, and ethambutol were determined in 26 ambulatory male patients (aged 49.5 +/- 9.9 yr) with tuberculosis. Rifampin and isoniazid were given individually or together, with or without ethambutol; studies were done after a single dose and after chronic administration. Under the study conditions, with large variability… CONTINUE READING