Pharmacokinetics of antipyrin, nifedipine, and diazepam in experimental myocardial infarction

Abstract

The pharmacokinetic parameters of lipid-soluble drugs are largely determined by the functiona~ ~tate of the microsomal monooxygenases of the liver [9]. Previous investigations have shown that acute myocardial infarction weakens hydroxylating activity and reduces the content of the main component of the monooxygenases, namely cytochrome P-450 [3]. However… (More)
DOI: 10.1007/BF00840935

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Cite this paper

@article{Shaparov2004PharmacokineticsOA, title={Pharmacokinetics of antipyrin, nifedipine, and diazepam in experimental myocardial infarction}, author={Valerii Shaparov and O. R. Grek and E. A. Anan'ev and Mikhail A. Kolpakov}, journal={Bulletin of Experimental Biology and Medicine}, year={2004}, volume={113}, pages={502-505} }