Pharmacokinetics of anti-tuberculosis drugs in children.

  title={Pharmacokinetics of anti-tuberculosis drugs in children.},
  author={G. Ramachandran and Agibothu Kupparam Hemanth Kumar and S. S. Swaminathan},
  journal={Indian journal of pediatrics},
  volume={78 4},
Tuberculosis (TB) is among the top 10 causes of death among children worldwide. Recent reports suggest that the currently recommended dosages of first-line anti-TB drugs are not adequate in children, particularly younger children. The objective of this review was to synthesize available pharmacokinetic data of anti-TB drugs in children from different settings that would help determine optimal doses of anti-TB drugs, in order to provide evidence-based recommendations. A PubMed database was… CONTINUE READING