Pharmacokinetics of a single bolus of propofol in chinese children of different ages.

@article{Shangguan2006PharmacokineticsOA,
  title={Pharmacokinetics of a single bolus of propofol in chinese children of different ages.},
  author={Wang Ning Shangguan and Qingquan Lian and Leon Aarons and Ivan Matthews and Zengshou Wang and Xiaolin Chen and Nick Freemantle and Fang Gao Smith},
  journal={Anesthesiology},
  year={2006},
  volume={104 1},
  pages={27-32}
}
BACKGROUND There is no information about the pharmacokinetic profile of propofol in Chinese children younger than 3 yr. This study was designed to determine a complete pharmacokinetic profile of a single dose of propofol in Chinese children of different ages. METHODS Arterial blood samples were obtained from 35 children with an American Society of Anesthesiologist physical status of I or II at 2, 4, 6, 8, 10, 20, 30, 45, 60, 90, 120, and 180 min after a single bolus intravenous injection of… CONTINUE READING