Pharmacokinetics of Total and Unbound Etravirine in HIV-1-Infected Pregnant Women.

Abstract

BACKGROUND Treatment of HIV-1-infected women during pregnancy protects maternal health and reduces the risk of perinatal transmission of HIV-1. However, physiologic changes that occur during pregnancy may affect drug pharmacokinetics. This phase IIIb, open-label study evaluated the effects of pregnancy on the pharmacokinetics of the nonnucleoside reverse… (More)

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