Pharmacokinetics of T-2 tetraol, a urinary metabolite of the trichothecene mycotoxin, T-2 toxin, in dog.

@article{Sintov1987PharmacokineticsOT,
  title={Pharmacokinetics of T-2 tetraol, a urinary metabolite of the trichothecene mycotoxin, T-2 toxin, in dog.},
  author={Amnon C. Sintov and Meir Bialer and Boris Yagen},
  journal={Xenobiotica; the fate of foreign compounds in biological systems},
  year={1987},
  volume={17 8},
  pages={941-50}
}
1. The urinary metabolites of T-2 toxin were identified and analysed quantitatively after i.v. administration to dogs. 2. A new routine assay for T-2 tetraol was developed and a pharmacokinetic study was carried out on this final hydrolytic metabolite of T-2 toxin. T-2 tetraol was excreted in urine for 2-3 days. Its 'sigma minus' plot demonstrated a significantly longer apparent half-life than its precursors (T-2 toxin and HT-2 toxin). This fact was explained by extraplasma binding causing… CONTINUE READING

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Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
Pharmacokinetics of T-2 tetraol , a urinary metabolite of the trichothecene mycotoxin , T-2 toxin , in dog .
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