Pharmacokinetics of Single‐Dose Rectal Zonisamide Administration in Normal Dogs

BACKGROUND Few medications are available for parental administration to animals with seizures. Rectal administration of medications is often used if the animal cannot be administered oral medications. HYPOTHESIS/OBJECTIVES To determine the pharmacokinetic differences in zonisamide when administered rectally in either of 2 vehicles and p.o. to dogs… CONTINUE READING