Pharmacokinetics of Selective Estrogen Receptor Modulators

  title={Pharmacokinetics of Selective Estrogen Receptor Modulators},
  author={K. Morello and Gregory T. Wurz and Michael W. DeGregorio},
  journal={Clinical Pharmacokinetics},
  • K. Morello, Gregory T. Wurz, Michael W. DeGregorio
  • Published 2003
  • Medicine
  • Clinical Pharmacokinetics
  • Selective estrogen receptor modulators (SERMs) are a class of compounds used to treat and prevent breast cancer and osteoporosis. SERMs currently approved for use in patients include tamoxifen, toremifene and raloxifene. These compounds are well tolerated in patients, and the most common adverse effects experienced in patients undergoing SERM therapy include vasomotor symptoms such as hot flashes and vaginal discharge. New SERMs currently under development for use in the treatment and… CONTINUE READING
    145 Citations

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