Pharmacokinetics of Sch 34343 in rats and dogs.

  title={Pharmacokinetics of Sch 34343 in rats and dogs.},
  author={Chao Shuang Lin and David Loebenberg and Marilyn Chung and E M Oden and J W Veals and H S Kim and Josephine Lim and C A Korduba and Richard D'Souza and Esther Moss},
  journal={The Journal of antimicrobial chemotherapy},
  volume={15 Suppl C},
The pharmacokinetics of 14C-Sch 34343 were studied in rats and dogs following intravenous and intramuscular dosing. In both species, it was rapidly absorbed after intramuscular dosing. The serum AUC for total radioactivity and for intact drug after intramuscular dosing were similar to those obtained after intravenous dosing. Following both routes of drug… CONTINUE READING