Pharmacokinetics of Rectal Drug Administration, Part I

@article{Hoogdalem1991PharmacokineticsOR,
  title={Pharmacokinetics of Rectal Drug Administration, Part I},
  author={Ewoud J. van Hoogdalem and Albertus G. de Boer and D. D. Breimer},
  journal={Clinical Pharmacokinetics},
  year={1991},
  volume={21},
  pages={11-26}
}
SummaryGenerally, oral administration is the route of choice in the daily practice of pharmacotherapy. However, in some circumstances this is impractical or even impossible (during nausea and vomiting or convulsions, in uncooperative patients and before surgery). In these cases, the rectal route may represent a practical alternative and rectal administration is now well accepted for delivering, for example, anticonvulsants, non-narcotic and narcotic analgesics, theophylline, antiemetics and… 
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