Pharmacokinetics of Cetamolol in Hypertensive Patients with Normal and Compromised Renal Function

@article{Skoutakis1988PharmacokineticsOC,
  title={Pharmacokinetics of Cetamolol in Hypertensive Patients with Normal and Compromised Renal Function},
  author={V. A. Skoutakis and S. Acchiardo and C. Carter and C. Ingebretsen and M. Klausner and D. Lee and M. Kraml},
  journal={The Journal of Clinical Pharmacology},
  year={1988},
  volume={28}
}
The efficacy, safety, and pharmacokinetic parameters of a 30‐mg oral dose of cetamolol hydrochloride (Betacor), a new synthetic cardioselective beta‐adrenoceptor antagonist, with intrinsic sympathomimetic activity, were evaluated by studying 32 hypertensive patients with normal renal function or different degrees of renal impairment. After administration of cetamolol, serial blood and urine sample collections, as well as vital sign determinations for the next 48 hours, were performed in all… Expand
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