Pharmacokinetics of Bupropion and Its Pharmacologically Active Metabolites in Pregnancy.

Abstract

Bupropion sustained release is used to promote smoking cessation in males and nonpregnant females. However, its efficacy as a smoking cessation aid during pregnancy is not reported. The pregnancy-associated changes in maternal physiology may alter the pharmacokinetics and pharmacodynamics of bupropion and consequently its efficacy in pregnant smokers… (More)

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Cite this paper

@article{Fokina2016PharmacokineticsOB, title={Pharmacokinetics of Bupropion and Its Pharmacologically Active Metabolites in Pregnancy.}, author={Valentina M Fokina and Meixiang Xu and Erik Rytting and S. Z. Abdel-Rahman and Holly West and Cheryl A. Oncken and S. M. Clark and Mahmoud Sid Ahmed and Gary D. V. Hankins and Tatiana N Nanovskaya}, journal={Drug metabolism and disposition: the biological fate of chemicals}, year={2016}, volume={44 11}, pages={1832-1838} }