Pharmacokinetics of (R,S)-Albuterol after aerosol inhalation in healthy adult volunteers.

@article{Anderson1998PharmacokineticsO,
  title={Pharmacokinetics of (R,S)-Albuterol after aerosol inhalation in healthy adult volunteers.},
  author={Paula J. Anderson and Xiao-fei Zhou and Phil Breen and L Gann and Tom Logsdon and Cesar M. Compadre and F. Charles Hiller},
  journal={Journal of pharmaceutical sciences},
  year={1998},
  volume={87 7},
  pages={
          841-4
        }
}
The pharmacokinetics of inhaled (R,S)-albuterol following pulmonary absorption were studied in healthy human subjects. Ten subjects (5 females and 5 males) inhaled two puffs (180 microg) of albuterol via a metered-dose inhaler and spacer device. All subjects were nonsmoking and had normal pulmonary function. Charcoal slurries were ingested to block gastrointestinal absorption of drug. Venous samples were obtained from each subject at thirteen time points from 0 through 12 h post dose. (R,S… CONTINUE READING

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