Pharmacokinetics in clinical practice. I. Concepts.

  title={Pharmacokinetics in clinical practice. I. Concepts.},
  author={Milo Gibaldi and Gerhard Levy},
  volume={235 17},
Important concepts of pharmacokinetics, such as the biologic half-life, clearance, and bioavailability of drugs, can be utilized to describe and predict the time course of drug concentrations in plasma as a function of dose and frequency of drug administration. In quantitative terms, they can serve to characterize the individuality of the patient, including… CONTINUE READING